Hyperbaric oxygen

 Hyperbaric oxygen therapy in radiation proctitis all are true except
A. Indicated in acute radiation proctitis but not in subacute or chronic radiation proctitis
B. Oxygen increases the growth of residual tumor and hence tumor should be completely
C. Complications include Parkinsonism, barotrauma
D. Usually 30-40 sessions are required for treatment

Answer free for all


Hyperbaric oxygen overcomes chronic tissue hypoxia in radiation damaged tissues and with repeated sessions induces growth of regenerative tissue, capillaries, and epithelium. Successful therapy may take multiple sessions.
 18 to 60 treatments

Ref Shackelford page 2211

HBO treatments for hypoxic wounds are usually delivered at 1.9 to 2.5 atm

for sessions of 90 to 120 minutes each. Treatments are given once daily, five to six times per week and should be given as an adjunct to surgical or medical therapies. Clinical evidence of wound improvement should be noted after 15 to 20 treatments. Read More ...

Familial Adenomatous polyposis

Q. All are false about adenomatous polyposis syndrome except
A. 25% do not have family history
B. Attenuated FAP has less than 100 polyps and delayed onset (50-55 yrs)
C. More than 20 rectal polyps have to be operated as there is high risk of Carcinoma
D. Attenuated FAP don’t have extracolonic manifestations and carry APC mutation

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Q True regarding CEA is  (AIIMS 2017 , JIPMER 2016) 

a) Low specificity

b) Falls after 1 week of surgery to baseline

c) Preoperative high value is good prognostic marker

d) Follow up, first test of CEA in 8-10 days followed by weekly tests thereafter

Another question on CEA can be seen here


Poor Prognosis in colon polyp

Q) All are poor prognostic factors in colonic polyp except?

a) Poorly diff in the head

b) Moderately differentiated polyp

c)  Involving the stalk

d) Margins positive


Poor prognostic factors in a polyp aare

1. histologically  poorly  differentiated invasive  carcinoma

2. cancer  cells  observed  in  the lymphovascular  spaces,  there  is  a  more  than  a  10%.......... 

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