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Surgery Multiple Choice Questions on Surgery of Esophagus

Q 8.Most valuable investigation for preoperative evaluation of extensive corrosive stricture is

a) Endoscopic ultrasound
b) Barium study
c) CT Thorax
d) Pharyngoscopy

Q9. Not an association between (PSC)  Primary sclerosing cholangitis and Ulcerative colitis (UC)
a) Inflamatory Bowel disease (IBD) seen in 70% of patients with PSC
b) Diagnosis of IBD occurs 8-10 years before PSC
c) Colitis is severe in patients with both PSC And UC as compared to UC alone
d) Risk of colon cancer is more when patients have both UC and PSC as compared to UC alone



Answers

6. a
Although Family history is important in colon cancers most of the cases are sporadic (70%)
Family history of CRC (15-20%)
HNPCC (5%)
FAP (<1%)
Reference Shackelford Surgery of Alimentary canal 6th edition page 2186

7. b
FAP is associated with osteoma of mandible and skull, sebaceous cysts, dermoid, desmoid tumors and mesenchymal hamartomas
Recurrence of colorectal tumors is not known after total colectomy


8.a

9. c
Colitis is less in patients who have both PSC and UC
The absolute cumulative risk of developing colorectal dysplasia/carcinoma in patients with both PSC and CUC was 9%, 31%, and 50% after 10, 20, and 25 years of PSC duration, respectively in a swedish studey. On the contrary, patients with CUC alone had 2%, 5%, and 10% absolute cumulative risk to develop colorectal dysplasia/carcinoma following 10, 20, and 25 years' history of CUC, respectively
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Q6. Which of these genetic risk factors has the highest association with colon cancers
a) Sporadic   
b) Past family history of colo rectal cancer
c) Hereditary Nonpolyposis colon cancer (HNPCC)
d) Familial Adenomatous Polyposis (FAP)


Q7. After total proctocolectomy with ileal pouch anal anastomoses what is the most common cause of death in patients with Familial Adenomatous Polyposis (FAP)
a) Gastric cancer
b) Periampullary carcinoma
c) Genito urinary cancers
d) Recurrence of colorectal cancer
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