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Imaging of Malignant diseases of liver
Hepatocellular carcinoma, fibrlamellar variant
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Imaging benign
diseases liver
Chlolecystitis
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Hepatocellular Carcinoma
It can be solitary, multifocal or diffuse

Ultrasound- It appears as a discrete lesion, either solid or multiple.
                    Small tumor ie (<3cm) are hypoechoic where as larger sized tumors are hyperechoic.
                    Ultrasound  has a very low sensitivity in differentiating a regenerating nodule from a tumor.
                    Presence of hypoechoic rim helps in differentiating a hepatocellular carcinoma from haemangioma.
                    Invasion of portal vein and hepatic vein may be seen.


Colour Doppler - It shows an arterial flow pattern in the thrombus.


Contrast Enhanced Ultrasound-- Shows Rapid peak enhancement in the arterial phase and (increased echogenicity) and washout (hypoechogenity) in the venous phase.



CT Scan- Non enhanced CECT shows- solitary or multiple low attenuating lesion
              Arterial phase- Intense enhancement through out the tumor with hypodense rim
              Venous phase- Rapid washout of contrast and lesion becomes hypodense to isodense
              Delayed Images - show the capsule and fibrous septa  as hyperdense.

MRI  Hypointense on T1W
          Hyperintense on T2W

Fibrolamellar hepatocellular carcinoma
Major clue to the diagnosis is central scarring and central stellate calcification.

Ultrasound- Lobulated heterogenous, hyperehoic mass
                    Scar is hyperechoic non shadowing area
              

CT scan --Well defined hypodense lesion
                 Stellate calcification seen in 50-60%
                 It shows hetergenous enhancement on arterial and portal venous phase and washout in delayed phase.
                

MRI - Hypointense on T1w and hyperintense on T2w
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