Interesting Questions in Surgery
Interesting Questions and Controversies in Surgery
Surgery Multiple Questions
Q What is radical esophagectomy?
A   It includes both two field and three field esophagectomy
     Two field esophagectomy
      For tumors of the middle or lower thoracic esophagus, the en-bloc specimen would include, in addition to the tumor-bearing organ, the pericardium anteriorly
       both pleural surfaces laterally,  thoracic duct and all other lympho-areolar tissue wedged posteriorly between the esophagus and the spine.
      Additionally, for tumors traversing the diaphragm, a 1-in cuff of diaphragm is excised circumferentially around the esophagus.
      The associated two-field lymphadenectomy includes en-bloc resection of all nodal groups between the tracheal bifurcation superiorly to the celiac axis inferiorly.
      Lymph node stations include
     
      Periesophageal, parahiatal, subcarinal, and aortopulmonary window nodes.
       In the abdomen, an upper abdominal and retroperitoneal node dissection is performed, and includes resection of the celiac, splenic, common hepatic, left gastric, lesser              curvature, and parahiatal nodes
Three field esophagectomy
40% of patients who had resected squamous cell esophageal cancer developed isolated cervical lymph node metastases
The additional third field of dissection included excision of the nodes along both recurrent nerves as they course through the mediastinum and neck, as well as a modified            cervical node dissection. The latter includes the nodes posterior and lateral to the internal jugular vein and an infraomohyoid node dissection bilaterally

     There is  substantial morbidity rates associated with three-field lymphadenectomy, recent research focuses on refining patient selection for this procedure. From mostly               retrospective studies, it can be shown that survival advantage may not be demonstrable for lower-third tumors], for patients who have positive nodes in all   three surgical               fields where intramural metastases are present, or in those who have five or more involved nodes
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Q Why AST and ALT get elevated in Acute Cholecystitis?
A   There are two reasons given in Sabiston text book of surgery which makes interesting reading
1. Direct contact of inflamed gallbladder with liver surface enciting a response
2. Sepsis in general brings about changes in heptocyte cell membrane


Q Differences between Non Cirrhotic Portal fibrosis and Extra hepatic portal vein obstruction

                                        NCPF                                                                          EHPVO

1. Etiology- At birth infection or a prothrombotic event  precipitates thrombosis in the portal vein or its radicals. It is NCPF if thrombosis occurs in Medium or small branch of Portal vein but it is EHPVO if the thrombosis is a major event and affects the major branch.
Also if a major thrombosis recanalises it may lead to NCPF.

2. pathology - In NCPF portal vein is thickened and dilated with thick sclerosed walls.
          
3. HPE- Obliterative porto venopathy ie subendothelial thickening of portal venous branches . There is intimal thickening of intrahepatic portal venous channels in NCPF

4. Wedged Hepatic venous pressure is normal or only slightly elevated in NCPF

5. Clinical features- young, low socio economic status, male, well tolerated episodes of upper GI bleed, hypersplenism in NCPF

6. Lab parameters show anemia and hypersplenism

7. Ultrasound- Ultrasonography is the investigation of choice. It shows a dilated and patent splenoportal axis with significantly thickened walls of the portal vein and its main branches.

             
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