a) Parenchymal cells

b) Ductal cells

c) Canalicular cells

d) Non parenchymal cells

a) Arterial bruit is seen in 80% cases of hepatocellular carcinoma (HCC)

b) 2/3rd of patients  present with signs of chronic liver disease

c) 5% of patients present with haemoperitoneum

d) none

a) Hypoglycemia

b) Hyponatremia

c) Hypercalcemia

a) alpha feto protein

b) carbohydrate antigen

c) alpha fucosidase

d) CA19-9

a) USG

b)CT

c)MRI

ANSWERS

21) b

Partial hepatectomy leads to proliferation of all populations of cells within the liver, including hepatocytes, biliary epithelial cells and endothelial cells. DNA synthesis is initiated in these cells within 10 to 12 hours after surgery and essentially ceases in about 3 days. Cellular proliferation begins in the periportal region (i.e. around the portal triads) and proceeds toward the centers of lobules.

Most of this rapid regeneration is due to mitotic division of preexisting differentiated liver cells, including hepatocytes, bile duct epithelium, and endothelial cells.

Since prolifeartion goes from periphery to centre duct cells are the first to get involved

22)d

None of the above is true-

Bruit is seen in 30%, haemoperitoneum in 10%, 1-10% with jaundice and 5 % with metastasis. Common presenting features are pain abdomen, abdominal  mass,  weight loss ascites etc

23)a

Other symptoms  are hypercalcemia and hypertrophic osteodystrophy

24) a

Alpha Feto protein is elevated in 55-95% of patients of hepatocellular carcinoma (HCC). High levels are seen in large and rapidly growing tumors. Also in HBSAg positive patients

25) a

Ultrasound is not very sensitive for liver tumors and it is difficult to distinguish in cirrhosis but it is the screening investigation of choice because of low cost.