Pharmacology

49) Drug causing hyperglycaemia
1) Glucocorticoids
2) Beta blockers
 
50) Furosemide, true is
1) Acts on PCT
2) Given by parental route only
3) Used in pulmonary edema
4) Causes mild diuresis
 
51) Thiazide causes A/E:
1) Hyperglycaemia
2) Increased calcium excretion
3) Increased blood uric acid levels
4) Used in CCF
 
52) Biphosphonates are used in A/E:
1) Hypercalcemia
2) Cancer
3) Osteoporosis
4) Hypervitaminosis D
 
53) Tryptans act through
1) 5HT1a
2) 5HT1b
3) 5HT1c
4) 5HT3
 
54) Therapeutic monitoring is required for A/E:
1) Phenytoin
2) Cyclosporine
3) Tacrolimus
4) Metformin
 
55) True abt protease inhibitors are A/E:
1) MDR-1 gene
2) Metabolized by hepatic enzymes
3) Drug interaction
4) Saquinavir has the most potent action on CYP3A4
 
56) Following drugs act on GABA-A except
1) Thiopentone
2) Midazolam
3) Zopiclone
4) Promethazine
 
57) Phenytoin all are true except:
1) Induces enzymes
2) Zero order kinetics at low dose
3) Half life increases with increasing dose
4) Highly protein bound
 
5 Which of the following drug binds most avidly to 5HT3
1) Granisetron
2) Ondansetron
3) Dolasetron
4) Palavosetran
 
59) Marker of acute hepatitis B:
1) Anti HBsAg
2) IgG Anti HBc
3) HBeAg
4) HBV DNA
 
60) Group of drugs not used for sedation but with AE of sedation is
1) Antihistaminics, antidepressants
2) Digitals, antiarrythmics
 
61) Fibrates all are true except
 
 
62) Benzodiazepines true is
1) Safer in overdose
2) Induce metabolism of other drugs
3) All have active metabolites
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