Disinfectants in Surgery

Q) All are true about disinfectants in surgery  except
A. Povidone iodine needs to dry up prior to its action
B. Alcohol disinfectants act against all organisms except clostridium difficile
C. Single dose of first generation cephalosporin should be givens prophylaxis for vascular
procedures and bladder catheterisation
D. Chlorhexidine is bactericidal, viricidal, fungicidal, and has rapid onset of action and persistent
duration.


Answer d

Povidone-iodine solution is used for surgical site preparation, it must be allowed to dry for microbicidal effect. 

Chlorhexidine is  a phenol which is  used in concentrations of 0.5% to 4.0% alone or in lower concentrations in combination with an alcohol as a skin antiseptic. ....

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CEA

Q True regarding CEA is  (AIIMS 2017 , JIPMER 2016) 

a) Low specificity

b) Falls after 1 week of surgery to baseline

c) Preoperative high value is good prognostic marker

d) Follow up, first test of CEA in 8-10 days followed by weekly tests thereafter

Another question on CEA can be seen here

Answer 

Physiology of biliary obstruction

Q) Infection in obstructive jaundice all are true except

a) There is loosening of hepatic tight junctions and cholangiovenous reflux

b) IgM production from liver cells decreased

c) Reduced bacteriostatic & bactericidal action due to decreased bile salts in bowel

Answer 

In  patients  with  long-standing  obstruction,  intrahepatic bile ductule  proliferation occurs with an increase in the length and tortuosity of the canaliculi. The  biliary  system  normally  has  a  low  pressure  (5  to  10  cm H2O);  however,  in  the  setting  of  complete  or  partial  biliary obstruction,  biliary  pressure  can  approach  30  cm  H2O. 

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