Retroperitoneal Sarcoma

Q) Which of the following about retroperitoneal sarcoma is true?

a) Angiosarcoma is the most common retroperitoneal sarcoma

b) Most common presentation is pain abdomen

c) Lymph node resection should be done even if no lymph nodes are seen on imaging (CT and MRI)

d) Radiation causes retroperitoneal sarcoma at an average of 10 years after exposure

Answer for all 

JClinImagingSci_2015_5_1_24_156135_f1 Retroperitoneal Sarcoma

 d) Radiation is a known risk factor which causes this condition mostly 10 years after exposure.

Other pre disposing conditions include 

  1. Von Recklinghausen's disease
  2. Li- Fraumeni's disease
  3. Hereditary Retinoblastomas

Most common retroperitoneal sarcomas are liposarcoma and leiomyosarcoma. 

Lymphomas and testicular tumors can also cause similar presentation. Pre operative biopsy is required in all cases because management may change.

Asymptomatic large abdominal mass is the most common presentation. Pain abdomen is seen in 50% of all cases

Other symptoms are 

1.GI hemorrhage

2. Weight loss

3. Limb edema

Metastasis can go in lungs and bones

 These tumors rarely have  metastases to lymph nodes and prophylactic lymph node excision is  not required.