Esophagus Cancer- Questions to answer

Q21) Which one of the following is not a management option in early esophageal cancer?

a) Photodynamic therapy

b) Endoscopic Mucosal resection

c) Argon plasma coagulation

d) Esophagectomy

Q22) Which of the following is the least common symptom of nutcracker esophagus?

a) Pain in chest

b) Dysphagia

c) Odynophagia

d) Regurgitation


21 d Esophagectomy

There is a recent term Endoscopically suspected Esophageal metaplasia (ESEM) seen with white light high resolution endoscopy. Management is PPI and repeat evaluation after 6-12 months

Once Barrett's esophagus is diagnosed, the further management depends on weather its a low grade or high grade dysplasia.

No dysplasia and barrett's segment < 3 cm - Endoscopic surveillance 5 years

No dysplasia and barrett's segment > 3 cm - 3 year surveillance with four quadrant biopsy every 2 cm

Indefinite dysplasia - Biopsy repeat 3-6 months

Low grade dysplasia - 6-12 months  endoscopic surveillance

HIgh grade dysplasia/Early esophageal cancer-

Special cases

i) age younger than 30 years at the time of Barrett's diagnosis

ii) a family history of Barrett's esophagus or esophageal cancer, 

iii) a segment of circumferential Barrett's esophagus greater than 6 cm

Endoscopic ablative therapy can be considered

Dysplasia and Invasive carcinoma

  1. No submucosal invasion - EMR followed by ablative management
  2. T1b or more (submucosal invasion) -Esophagectomy

EMR, PDT and APC can be done for T1a lesion

22)  d

 Nutcracker esophagus is a hyper contractile disorder of the  esophagus in which there is excessive contractility of the esophagus. There are high amplitude peristaltic contractions in the body of esophagus.

It is the most common motility disorder of the esophagus.

It can occur in all age groups and is of equal distribution in both sex.

Nutcracker esophagus symptoms

  1. Chest pain
  2. Dysphagia
  3. Painful deglutition (Odynophagia)

Acording to the Chicago classification 

 There is  subjective complaint of chest pain with at least one swallow showing a distal contractile integral greater than 8000 mm  Hg with single or multi­peaked contractions on HRM. The LES pressure is normal, and relaxation occurs with each wet swallow


  1. Avoid trigger inducing foods such as caffeine
  2. Calcium channel blockers, Nitrates, Antispasmodics
  3. Esophageal dilatation in some cases