Jejunum

Enteropathy in T cell lymphoma

October 30, 2019 admin

Q. Not true about enteropathy in T cell lymphoma

a) It is an variant of intestinal lymphoma mainly in jejunum and ileum

b) Associated with coeliac disease

c) Perforation is frequently seen with ETL (Enteropathy T cell lymphoma)

d) This type of lymphoma is common

Questions 1-6 Jejunum (free)

Ans. d

Enteropathy T cell lymphoma is an unusual variant of intestinal lymphoma. It is associated with celiac disease and responds to gluten free diet. It has a higher rate of perforations because of circumferential ulcers. It is commonly seen in jejunum and ileum

Ref- Schakelford Surgery of Alimentary canal pg 1205

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Indications of Small Bowel transplant

September 28, 2019September 28, 2019 admin

Q ) One of the following is not an indication for small bowel transplant

a) Impensing liver failure by PNALD

b) Multiple thromboses of central veins

c) Single episode of catheter-related infection requiring hospitalization in any year

d) single episode of fungal line infection

Ingested foreign bodies

June 19, 2019 admin

Q) False statement about ingested foreign bodies is

a) Conservative management in most patients

b) Cathartic agents are part of conservative management

c) Sharp objects can cause perforation

d) Laparotom is indicated for obstruction

Contra Indication of stricturoplasty

June 18, 2019 admin

Q) All are contraindications of stricturoplasty in crohn's disease of small intestine except?

a) Perforation of intestine

b) Fistula or abscess at stricturoplasty site

c) Multiple strictures in short segment

d) Albumin < 2 g/dl

Intussusception in childhood

May 8, 2019May 8, 2019 admin

Q) Most common intussusception in children is

a) Ileocolic

b) Ileoileal

c) Ileoileocolic

d) Colocolic

Answer for premium

GIST

April 15, 2019April 24, 2019 admin

Q) True statement regarding GIST is (AIIMS 2019)

a) 80% of GIST arise from stomach

b) ILeal GIST is resistant to Imatinab

c) Leiomyosarcomas do not express CD 117

d) Prognosis of GIST does not depend on the site of lesion

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They can appear anywhere within the GI tract, although they are usually found in the stomach (40% to 60%), small intestine (30%), and colon (15%).

Development of imatinib mesylate has significantly altered previous treatment strategies. Imatinib mesylate is a tyrosine kinase inhibitor that blocks the unregulated mutant c-kit tyrosine kinase and inhibits the BCR-ABL and PDGF tyrosine kinases.

Current guidelines suggest that patients with high-risk disease should receive 3 years of adjuvant therapy at all sites

Sabiston page 1280

Ileal GIST are more malignant than stomach GIST

Leiomyosarcomas

Among the gastric tumors, there were no examples of true leiomyosarcomas, whereas there were four small intestinal, four colonic, and two rectal tumors that histologically showed features of differentiated smooth muscle cells with blunt-ended nuclei and eosinophilic, sometimes granular, cytoplasm. These tumors were, by definition, all positive for SMA, and seven also were positive for desmin. Although all leiomyosarcomas were generally negative for CD117, scattered large neoplastic spindle cells (less than 1% of tumor cells) in two intestinal leiomyosarcomas showed strong cytoplasmic positivity; these four tumors were negative for CD34.

Ref https://www.nature.com/articles/3880210