Isolated limb perfusion

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Q) False about isolated limb perfusion in Soft tissue sarcoma (AIIMS onco 2021) 

a) MELPHALAN with hyperthermia is most effective 

b) Real time drug assay to monitor drug leak

c) Soft tissue fibrosis or, necrosis can occur

d) Used for recurrent melanoma with in transit metastasis

HIPEC in colorectal cancer

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Q) Agent NOT used in HIPEC in CRC
a) Mitomycin

b) cisplatin

c) oxaliplatin

d) Paclitaxel

 

Ovarian Cancer risk factors

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Q  ) Not protective in ovarian cancer? (# Gynae onco) 

a) Nulliparity

b) 5 yrs of OCP use

c) Breastfeeding

d) Tubal ligation

Ans10 a ) Nulliparity

Risk factors are

a) Increased age (peak age is 70 years),

b) Nulliparity

c) Early menarche, late menopause, delayed childbearing, and

Protective are

Both tubal ligation and salpingectomy have demonstrated a protective effect against the development of epithelial ovarian cancer, as
has the use of oral contraceptives for more than 5 years.

Ref Anderson page 862

 

Thymic Carcinoma

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Q) SVC syndrome with Thymic Carcinoma stage ( WHOB3) WHat will be the management? (#Lung Onco)

A)Chemo radiotherapy followed by surgery

b) Definitive chemoradiotherapy

c) Chemotherapy followed by surgery and radiotherapy

d) Surgery Alone

Hormonal levels

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Q) Male patient comes with Gynecomastia, Blindness and nipple discharge? Which hormone level will you do (# 

a) Testosterone

b) Estrogen

c)  Prolactin

d)  BHCG

 

 

Sarcoma with early lymph node spread

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Q) Soft tissue sarcoma  with  early lymph node metastasis is (#AIIMS onco 2021  # Soft tissue sarcoma)

a) Pleomorphic sarcoma
b) MFH
c) Angio sarcoma

d) all

Ans c)

In Sarcoma lymph node metastasis is rare in (<5%), except in a few histologic subtypes such as
1. epithelioid sarcoma

2. rhabdomyosarcoma

3. clear-cell sarcoma,

4.angiosarcoma

5.Undifferentiated pleomorphic sarcoma (UPS).

Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice