Q) In Crohns disease of duodenum , patient has a duodenal abscess which is drained. He develops a fistula with ileal communication. Surgery with the least chance of success would be
a. Ileal reaction and duodenal bypass
b. Ileal resection an dudodenal HMplasty c. Ileal freshen and closure d. Duodenum vertical closure
Q. Which of the following hormones are not released in duodenum?
a) Gastrin
b) Motilin
c) Somatostatin
d) Pancreatic YY
4. d Peptide YY is released from ileum.
Gastrin - G cells stomach Motilin- M cells from duodenum and jejunum Somatostatin - D cells in pancreas, stomach and duodenum
Somatostain is an inhibitory hormone and inhibits most of the things
Secretin is released by acid in the duodenum and stimulates pancreatic fluid and bicarbonate secretion, leading to neutralization of acidic chyme in the intestine. Secretin also inhibits gastric acid secretion and intestinal motility. LES pressure is decreased by Secretin, CCK, Somatostatin and VIP
Q) What is the Surgery in FAP patient after colectomy for ampullary adenoma Stage IV
a)Classic Whipple b) Pancreas preserving duodenectomy c) Transduodenal excision d) endoscopic excision
Answer is free for all
b)
Duodenal cancers are the third most common (10%) cause of death in FAP after CRC and desmoid disease.
Duodenal adenomas 100% incidence
tendency to progress to cancer.
The severity of duodenal adenomatosis predicts the chances of duodenal cancer, Spigelman staging system that is based on
adenoma number, size, and histology
Patients with stage 0 disease (no adenomas) can be surveyed again in 5 years.
Stage I patients can be surveyed in 3 years;
stage II in 1 year;
stage III in 6 months
and stage IV is an indication to consider surgery. 36 % progress to cancer- Surgery is pancreas preserving duodenectomy
A Whipple is indicated for a duodenal cancer that is definitively operable
Duodenal adenomas can be treated by snare polypectomy or by transduodenal polypectomy. Ampullary adenomas can be treated by endoscopic mucosal resection or surgical ampullectomy