Q) Which of the following is Not a risk factor for pouchitis post IPAA in ULcerative colitis
A) Smoking B ) NSAIDs use post op C) Elderly patients D) UC with extra intestinal manifestation
Pouchitis is the complication of Ileal Pouch Anal Anastomosis (IPAA) for Ulcerative colitis. The incidence of pochitis for the same proedure for familial Adenomatous polyposis is less than 10% but for ulcerative colitis can go as high as 50%.
Risk factors for development of pouchitis are
Previous extra intestinal manifestations of IBD especially arthritis
ANCA positive cases of UC
NOD2insC positive patients
Smoking prevents the development of puchitis after IPAA in ulcerative colitis.
5. Other reported factors that may associate with pouchitis include extent of UC, thrombocytosis,and PPI use with NSAId
a) VBG produces less weight loss when compared to RYGB
b) Jejuno-ileal by-pass not done nowadays.
c) Dumping is due to non- compliance of dietary advice
d) LAGB requires once a 4-6wk follow up
Calorie restriction is responsible for long term weight loss and its beneficial effects such as control of diabetes, dyslipidemia, hypertension and other metabolic abnormalities.
Restrictive procedures are LSG and LAGB which decrease the appetite and induce early satiety.
The RYGB (ROUX en Y gastric bypass ) is a malabsorptive procedure with long term sustained weight loss.
Mechanism of weight loss after bariatric surgery
Ghrelin is orexigenic gut hormone, which increases appetite. After food intake ghrelin levels fall and appetite decreases.
After restrictive surgery such as LYGB and LSG, ghrelin levels fall and appetite decreases.
Vertical Banded Gastroplasty (VBG) This procedure has been abandoned in favor of other operations because of poor long-term weight loss, a high rate of late stenosis of the gastric outlet, and a tendency for patients to adopt a highcalorie liquid diet, thereby leading to regain of weight. Choice a is correct
Q. Least common complication of Meckel's diverticulum (NEET 2018)
Answer is free 7) c Neoplasm
The most common clinical presentation of Meckel’s diverticulum is gastrointestinal bleeding, which occurs in 25% to 50% of patients who present with complications
intestinal obstruction occur as a result of a volvulus of the small bowel around a diverticulum associated with a fibrotic band attached to the abdominal wall, intussusception, or, rarely, incarceration of the diverticulum in an inguinal hernia (Littre hernia)
Diverticulitis accounts for 10% to 20% of symptomatic presentations.
Neoplasms can also occur in a Meckel’s diverticulum, with NET as the most common malignant neoplasm (77%). Other histologic types include adenocarcinoma (11%), which generally originates from the gastric mucosa, and GIST (10%) and lymphoma (1%).