Q Which of the following statement about hepatic adenoma is CORRECT?
a) It is more common in males
b) Ct shows a central stellate scar
c) Associated with cirrhotic liver
d) Risk of rupture and fatal hemorrhage is present
Giving a clinical scenario of Hepatic Adenoma
A 37 year old lady presents with right upper quadrant pain and nausea. She is otherwise well and her only medical therapy is the oral contraceptive pill which she has taken for many years with no ill effects. Her liver function tests and serum alpha feto protein are normal. An ultrasound examination demonstrates a 4cm non encapsulated lesion in the right lobe of the liver which has a mixed echogenicity and heterogeneous texture.
Q) Most common anomaly of hepatic artery noted during liver resection is a. Accessory right hepatic artery originating from superior mesenteric artery b. Replaced right hepatic artery originating from superior mesenteric artery c. Accessory left hepatic artery originating left gastric artery
d. Replaced left hepatic artery originating from left gastric artery
Q) False about vascular occlusion for hepatic surgery A. Portal triad clamping along with clamping of supra hepatic and infra hepatic IVC allows adequate bleeding control B. Prolonged intermittent clamping is usually used in longer surgeries C. Portal triad clamping can be done for 60 minutes under normothermia D. Liver tolerates vascular clamping well
Ans b is false, Short intermittent clamping is better
Hepatic vascular exclusion (HVE) combines total inflow and outflow vascular occlusion of the liver. Total isolation of the liver
from the systemic circulation is intended during resection of large tumors adjacent to or involving the major hepatic veins
and/or the IVC. ( BG 1619)
Intermittent inflow occlusion (Pringle, 1908) to control blood flow to the remnant, usually maintaining inflow occlusion for
periods of 15 minutes, interspersed by 5 minute periods of relief to allow perfusion of the remnant and decompression of
The superiority of intermittent inflow occlusion versus continuous or total occlusion is now widely accepted
According to the Cochrane database, in elective resection, intermittent portal triad clamping seems better than continuous clamping, especially in patients with diseased parenchyma. Therefore, intermittent triad clamping could be recommended as the “gold
standard” method of clamping
Clamps are applied for up to 60 minutes in patients with normal liver ( BG 1619)
c) is true A number of studies have
established that ≤ 90 min of complete PTC is safe in normal livers. Nonetheless, many surgeons will not clamp the inflow continuously for > 45 min because of concern about occult liver damage and most resections can be accomplished within this time frame.
d) is true Although the liver is relatively resistant to periods of warm ischaemia, it is vulnerable to anoxic conditions and may be more severely vulnerable if it has been chronically damaged by either cirrhosis or chemotherapy.