MCQ on General onco

Q) WHich is not a invasive mechanism of cancer cells invasion ?

a) Rise in interstitial pressure in the tissue

b) Dissolution of extracellular matix

c) Mobility of cells to Invade

d) Extra cellular matrix dissolution is due to  physical factors

Ans d 

Cancer cells secrete collagenases and proteases that chemically dissolve any extracellular boundaries
They also express  of cell-surface molecules called integrins

Three main mechanisms of cancer cells  that  facilitate invasion are

(1) Rise in the interstitial pressure within a tissue

2. They secrete enzymes that dissolve extracellular matrix

3. Acquire mobility

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