Q) Not a malignancy associated with lymphoedema? (#Skin tumors)
Oncosurgery
Genes and Cancers
In This post I will be adding most commonly associated genetic abnormalities and changes
MEN2 syndrome is caused by gain of function mutations in the RET gene.
Li-Fraumeni syndrome is associated with mutation of P53.
Mutations in p16 is associated with melanomas, pancreas, esophagus, head and neck, stomach, breast, and colon.
BRCA1 is associated with breast and ovarian carcinoma.
Soft tissue sarcoma with lymph node
Q) Which of the following soft tissue sarcoma (STS) associated with least lymph node metastasis:-
A. Fibrosarcoma
B. MFH
C. Epitheloid sarcoma
D. Rhabdomyosarcoma
Malignancy risk factors in IBD
Q) WHich is not a risk factor for malignancy in inflammatory bowel disease?
a) >50% crohn disease in colon
b) PSC
c) Old age of onset
d) use of Infliximab
HPV Vaccine
Q) Not true about HPV vaccine (#AIIMS onco 2020 Jun)
A. Can be useful even in already infected women
B. Can prevent Ca Cervix in unimmunized individuals
C. Bivalent and quadrivalent vaccine are available
d) Antibody response is lifelong
CDH 1 gene
Q) CDH 1 gene is associated with which cancer
a) Breast
b) Colon
c) Prostate
d) Renal