10 Questions on important onco Surgery Drugs

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Q1. Which of the following agents causes hemorrhagic cystitis?

a. Bleomycin

b. 5-fluorouracil

c. Cisplatin

d Cyclophosphamide

Ans d

Bleomycin can cause pulmonary fibrosis

Cisplatin - Ototoxicity, Neurotoxicity, Nephrotoxicity

5 FU - Mucositis, dermatitis and cerebellar dysf(x)

Q2. The most common complication of Bevacizumab is
a) hypertension
b) Hyperglycemia
c) Rashes
d) Gastrointestinal perforations

 2 a

The most common complication of bevacizumab is hypertension, requiring treatment (with routine oral antihypertensives) in approximately 10% of patients. Of more serious concern are two rare but serious complications: gastrointestinal perforation and arterial thromboses. Overall, 1.5% of patients receiving bevacizumab experienced a perforation in the gastrointestinal tract.

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