Q 41) Eosinophilic esophagitis - all are true except?
A.Most common presenting symptom is Dysphagia
B .Stricture develops in proximal esophagus
C . IL4 plays major role in eosinophil recruitment
D. Diagnosis established by Endoscopic biopsy
Q 43) Which has no part in management of corrosive injury of esophagus?
a) Repeated Endoscopies routinely
b) Esophagectomy in some cases
c) Early emergency surgery routinely
d) Steroid use routinely
Because IL 5 plays major role in eosinophil recruitment...
So immunotherapy against IL5 used in esonophilic esophagitis
Bailey page 1101 27th edition
Ref Bailey page 1097
Other than the need for emergency surgery for bleeding or perforation, elective oesophageal resection should be deferred for at least 3 months until the fibrotic phase has been established.
Oesophageal replacement is usually required for very long or multiple strictures. Resection can be difficult because of perioesophageal inflammation in these patients.
Regular endoscopic examinations are the best way to assess stricture development (Figure 62.12). Significant stricture formation occurs in about 50% of patients with extensive mucosal damage
corrosives, can cause significant pharyngolaryngeal oedema
In unusual circumstances, e.g. with extensive necrosis after corrosive ingestion, emergency oesophagectomy may be necessary.
Bailey 27th page 1075