Pancreas transplantation is typically performed for individuals with Type 1 diabetes who also have end-stage renal disease, often requiring kidney dialysis. This combination of kidney failure and Type 1 diabetes makes pancreas transplantation a viable treatment option.
SPK is the most frequently performed procedure for patients with type 1 diabetes and renal failure due to diabetic nephropathy.
There is a small population of patients with type 1 diabetes with renal failure due to primary renal disease or non-diabetic causes and they are also included in this group.