Q) Infection in obstructive jaundice all are true except
a) There is loosening of hepatic tight junctions and cholangiovenous reflux
b) IgM production from liver cells decreased
c) Reduced bacteriostatic & bactericidal action due to decreased bile salts in bowel
In patients with long-standing obstruction, intrahepatic bile ductule proliferation occurs with an increase in the length and tortuosity of the canaliculi. The biliary system normally has a low pressure (5 to 10 cm H2O); however, in the setting of complete or partial biliary obstruction, biliary pressure can approach 30 cm H2O.
Physiology of biliary obstruction