Q) Infection in obstructive jaundice all are true except

a) There is loosening of hepatic tight junctions and cholangiovenous reflux

b) IgM production from liver cells decreased

c) Reduced bacteriostatic & bactericidal action due to decreased bile salts in bowel

Answer 

In  patients  with  long-standing  obstruction,  intrahepatic bile ductule  proliferation occurs with an increase in the length and tortuosity of the canaliculi. The  biliary  system  normally  has  a  low  pressure  (5  to  10  cm H2O);  however,  in  the  setting  of  complete  or  partial  biliary obstruction,  biliary  pressure  can  approach  30  cm  H2O. 

Read on........

Physiology of biliary obstruction
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