Q) Not an important prognostic factor in Carcinoma thyroid (JIPMER) ?
A. Age
B. Completeness of resection
C. Multicentricity
D. Extra thyroid extension
Ans c In thyroid carcinoma, important prognostic factors include age (younger patients tend to have a better prognosis), completeness of resection (as complete removal of the tumor affects outcomes), and extra-thyroid extension (invasion beyond the thyroid worsens prognosis). However, multicentricity (the presence of multiple tumor foci within the thyroid) is generally not considered a major prognostic factor. Most of the papillary carcinoma are multicentric any way As per AGES And AMES criteria. HIgh risk - Male. Age more than 40 years, Size more than 4 cm, Capsular or extra thyroid extension, Regional or distant metastasis and poor differentiation Low Risk - Well differentiated less than 2 cm. Age benefit is extended to 50 yrs in women IN younger patients (<45 years old), the presence of lymph node metastases had no effect on the excellent overall survival, but the presence of lymph node metastases increased the risk of death by 46% in patients older than 45 The presence of lymph node metastasis in patients with contained intrathyroidal primary papillary carcinoma also does not affect If there is gross or microscopic extension of a primary PTC through the thyroid capsule, a poor prognosis and
long-term survival.
possibly a higher rate of lymph node metastasis may be anticipated.