Response to chemotherapy in Carcinoma Esophagus

Q) A patient with carcinoma lower 1/3 of esophagus, receives chemo Radiotherapy and dysphagia shows complete response. What is the next step in management

a) Reassure

b) Follow with CT scan every  6 months 

c) Esophagectomy

d) EUS to look for residual disease


 Ans c

Clinical trials and meta‐analyses have shown that a CRT + surgery regimen could significantly improve the survival of locally advanced esophageal carcinoma patients compared to surgery alone

Endoscopic biopsy, endoscopic ultrasonography, MRI (at various sequences), and PET‐CT all had shortcomings for evaluating cCR and the therapeutic effect of nCRT.