Introduction-
Topics we will cover
- Mean, Median, Mode, Range, Variance, and Standard Deviation.
-
- Hypothesis Testing (Null vs Alternative Hypothesis).
- Confidence Intervals.
- P-values and significance level.
- Types of errors (Type I and Type II).
-
- Continuous vs Discrete Data.
- Nominal, Ordinal, Interval, and Ratio Scales.
- Examples from surgical data (e.g., number of complications, surgical outcomes).
Study Designs in Surgical Research
-
- Randomized Controlled Trials (RCTs): Discuss their gold standard role in clinical research.
- Cohort Studies: Describe prospective and retrospective cohort studies.
- Case-Control Studies: What they are and when to use them.
- Cross-sectional Studies: Applications in surgery.
- Systematic Reviews and Meta-Analyses: Their importance in evidence-based medicine.
-
Statistical Tests in Surgery
- T-tests and ANOVA: When to use them to compare means (e.g., comparing recovery times between two surgical techniques).
- Chi-square Tests: Used to analyze categorical data (e.g., surgical complications).
- Regression Analysis: Understanding relationships between variables (e.g., age and surgical outcome).
- Survival Analysis: Kaplan-Meier curves, Cox proportional hazards model, and their use in analyzing surgical outcomes and patient survival.
Interpreting Results
- Understanding P-values and Confidence Intervals.
- Risk Ratios, Odds Ratios, and Hazard Ratios: Their use in surgery statistics.
- Effect Size: How it informs clinical relevance in surgical studies.
- Bias and Confounding: How they affect statistical results and their interpretation in surgery.
Practical Application
- How to Read a Surgical Study: What to focus on (study design, sample size, statistical significance, etc.).
- Statistical Software: Introduce common tools used in medical research (e.g., SPSS, R, Excel).
- Case Studies: Examples of statistical applications in surgery (e.g., evaluating the effectiveness of a new surgical technique).
Common Pitfalls in Surgical Statistics
- Overgeneralization of results.
- Misinterpretation of statistical significance vs clinical significance.
- The importance of sample size.
- The potential for bias in data collection.