Dumping Syndrome – Surgery Superspeciality MCQS

Q) What is the mechanism of action of Octreotide in dumping syndrome ?

a) Acceleration of gastric emptying

b) Shortening of small bowel transit time

c) Inhibition of endocrine secretions

d) All the above

Answer: C

Octreotide alleviates both early and late dumping symptoms through inhibition of hormone mediators.
It also delays gastric emptying time and inhibits splanchnic vasodilation.

Shack, 8th, 722.

These peptides not only inhibit gastric emptying but also affect small bowel motility so that intestinal transit of the ingested meal is prolonged.

Sabistan, 21st, 1217.

Snippets

Late dumping occurs 1 to 3 hours after a meal and is less common.
The basic defect of late dumping is also rapid gastric emptying; however, it is related specifically to carbohydrates being delivered rapidly into the proximal intestine.