Q) Fibrolamellar HCC is associated with? ( #NEET Onco Questions 2020)
✅ Correct Answer: a) Young age
🔍 Explanation:
- Fibrolamellar Hepatocellular Carcinoma typically affects younger patients without underlying cirrhosis.
- It is often well-demarcated, encapsulated, and contains a central fibrotic scar.
- Prognosis is better than classic HCC due to higher resectability, absence of chronic liver disease, and a more indolent behavior.
- Long-term survival can be expected in ~50–75% of patients.
- However, lymph node metastasis **can occur**, and when present, is associated with poorer outcomes.
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🔍 Explanation:
- Fibrolamellar Hepatocellular Carcinoma typically affects younger patients without underlying cirrhosis.
- It is often well-demarcated, encapsulated, and contains a central fibrotic scar.
- Prognosis is better than classic HCC due to higher resectability, absence of chronic liver disease, and a more indolent behavior.
- Long-term survival can be expected in ~50–75% of patients.
- However, lymph node metastasis **can occur**, and when present, is associated with poorer outcomes.
👉 Explore more Liver MCQs