Primary sites within the pharynx (i.e., nasopharynx, oropharynx, and hypopharynx) and supraglottic larynx are particularly high risk.
The oral cavity has an intermediate risk,
whereas the glottic larynx, nasal cavity, and paranasal sinuses are low risk. Other predictors of risk of metastases are higher T stage and thickness (in case of oral cavity cancers).