Q) The sensitivity and specificity of sestamibi for parathyroid localization are reported to be 79% and 90%, respectively. Which of the following best describes a potential source of false positives in sestamibi imaging? Theme from mock test on 16.2.25 #parathyroid
A) Parathyroid adenomas in patients with hyperparathyroidism B) Thyroid nodules with high oxyphilic content, such as Hürthle cell nodules C) Low mitochondrial content in thyroid tissues D) Parathyroid glands in normal positions
Q) Which is not a feature of primary hyperparathyroidism?
a) Increase Parathormone
b) Increase Calcium
c) Decreased phosphate
d) Dystrophic calcification
Ans d
Clinical features of Hyperparathyroidism are
Subperiosteal bone erosions
Primary Hyperthyroidism is defined as hypercalcaemia in the presence of an unsuppressed and therefore relatively, or absolutely, elevated PTH level. Elevated calcium and elevated PTH are important in diagnosis of PTH
The presence of kidney stones remains the most common clinical manifestation of symptomatic PHPT.
It is associated with a low serum phosphate in the setting of normal creatinine and vitamin D levels
Some uncommon disorders associated with hyperparathyroidism include
peptic ulcers, pancreatitis, and bone disease
central nervous system symptoms
Causes of Primary Hyperparathyroidism are
Parathyroid Adenoma -75% (can be localised by Sestamibi scanning)
Management of primary hyperparathyroidism
Patients with symptomatic primary hyperparathyroidism as manifested by kidney stones, renal dysfunction, or osteoporosis should undergo parathyroidectomy.
If the patient is asymptomatic and detected to have high parathyroid levels then surgery is done only if
