Q) Which of the following thyroid cancers do not take up radio active iodine
a) Medullary carcinoma thyroid
b) Papillary carcinoma
c) Follicular carcinoma
d) Hurthle cell carcinoma
Free Answer
a - Medullary carcinoma
Medullary carcinoma of the thyroid is a tumor that arises from the C cells ie the parafollicular cells and not from cells of thyroid follicles.
These are not TSH dependent and hence do not take up radioactive iodine
Hurthle cell carcinoma is a variation of follicular carcinoma only.
In these tumors lymph node involvement is about 60%
Bailey page 769
