Q1 ) Scar constriction is facilitated by ? A. Myofibroblasts B. Neutrophils C. Granuloma formation D. Macrophages
Ans a Myofibroblasts
Myofibroblasts are specialized cells that play a key role in wound healing and scar formation. They have contractile properties, which help in the constriction and closure of the wound during the healing process. Myofibroblasts pull the edges of the wound together, contributing to the reduction in wound size and the formation of a mature scar.
In the later stages fibroblasts convert into myofibroblasts which have a contractile phenotype and therefore help in contracting the wound.
Immature fibroblasts, though able to adhere to the ECM, do not have this ability.
Q) Longest phase of wound healing A. Inflamatory B Haemostasis C. Regeneration D. Remodeling
Ans D
Remodeling is the Longest phase of the healing process and may last up to one year (or longer). During this phase fibroblasts become
differentiated (myofibroblasts) and these facilitate wound contraction. Collagen fibres are remodeled. Microvessels regress
leaving a pale scar.
