Dieulafoy's lesion of the stomach is not an uncommon cause of upper GI bleeding. Its incidence in all patients with upper GI bleed range from 0.3 to 7%. The cause of such bleeding is a large tortuous vessel in submucosa which leads to ulceration of the over lying mucosa. The lesions occur at 6-10 cm from the cardia near the GE junction. Endoscopy is the diagnostic modality of choice and lesion is controlled by electrocoagulation, heatre probes or photo coagulation
Ref Sabiston 19th edition page 1222
0.2-0.6 g of bile salts are secreted by liver each day in the form of cholic acid and dexoy cholic acid.
Only 5% of bile salt is excreted per day and 95% is absorbed by the portal vein
Bile is stored and concentrated in the gall bladder
Gall bladder fills by retrograde mechanism by contraction of sphincter of oddi.
Haematogenous route is the most common route for acquiring splenic abscess (70%). Risk factors inculde polycythemia vera, malignancies, IV drugs etc. Unilocular splenic abscess has mortality rates of 15-20% and multiloculated abscess about 80%. Typical symptoms are fever, pain abdomen, pleuritic chest pain. Splenomegaly is uncommon.
Epiphrenic diverticulum is a lower esophageal diverticulum with in 10 cm of gastro esopheal junction (GEJ) Most of these diverticula are secondary and false due to associated motor disease such as Diffuse esophageal spasm (DES) or Achlasia. (Read more about Achlasia Cardia here) Unlike the middle esophageal divertula these are not traction diverticula. These are most commonly seen on the right side.
Most of these are asymptomatic and treatment is required only if they cause chest pain (due to DES) or regurgitaion or aspiration.
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